Article

Liver Sinusoidal Endothelial Cells in the Regulation of Immune Responses and Fibrosis in MASH Liver Disease

2025-01-08

Abstract excerpt

Liver Sinusoidal Endothelial Cells (LSECs) play a crucial role in maintaining liver homeostasis, regulating immune responses, and regulating fibrosis in liver diseases. This review explores the unique functions of LSECs in liver pathology, particularly their roles in immune tolerance, antigen presentation, and the modulation of hepatic stellate cells (HSCs) during fibrosis. LSECs act as key regulators of immune ba...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 256fc98f-7fdf-54b8-be23-c35e4a479942
DOI: 10.20944/preprints202501.0638.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Liver Sinusoidal Endothelial Cells in the Regulation of Immune Responses and Fibrosis in MASH Liver DiseaseDOI 10.20944/preprints202501.0638.v1Read

SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis.Semantic proximity Read

RISING STARS: Liver sinusoidal endothelial transcription factors in metabolic homeostasis and diseaseSemantic proximity Read

The evolving role of liver sinusoidal endothelial cells in liver health and diseaseSemantic proximity Read

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read

Regulation of Hepatic Stellate Cell Phenotypes in Metabolic Dysfunction-Associated Steatohepatitis.Semantic proximity Read

Matrix Stiffness Regulates Liver Sinusoidal Endothelial Cell Function Mimicking Responses in Fatty Liver DiseaseSemantic proximity Read

Mapping vascular plasticity in liver fibrogenesis identifies novel fibrosis-associated endothelial cells in early-stage liver diseaseSemantic proximity Read

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosisSemantic proximity Read

Current Insights into Liver Fibrosis: Epidemiological Patterns, Etiopathogenesis, Clinical Correlates, and Research AgendaSemantic proximity Read

Single-cell transcriptome reveals a novel mechanism of C-Kit+-liver sinusoidal endothelial cells in NASHSemantic proximity Read

Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment conceptsSemantic proximity Read

Decoding liver fibrogenesis with single-cell technologiesSemantic proximity Read