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Article

SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis.

BioMed research international - 1 Jan 2017

Natarajan Vaishaali, Harris Edward N, Kidambi Srivatsan

Abstract excerpt

Liver fibrosis is a wound-healing response to chronic liver injury such as alcoholic/nonalcoholic fatty liver disease and viral hepatitis with no FDA-approved treatments. Liver fibrosis results in a continual accumulation of extracellular matrix (ECM) proteins and paves the way for replacement of parenchyma with nonfunctional scar tissue. The fibrotic condition results in drastic changes in the local mechanical,...

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Identifiers

PMID: 28293634
DOI: 10.1155/2017/4097205
PMCID: PMC5331310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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