Significant Association Between the MiR146a Genotypes and Susceptibility to Childhood Acute Lymphoblastic Leukemia in Taiwan.

doi:10.21873/cgp.20178

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Significant Association Between the MiR146a Genotypes and Susceptibility to Childhood Acute Lymphoblastic Leukemia in Taiwan.

Cancer genomics & proteomics - 1 Jan 2000

Pei Jen-Sheng, Chang Wen-Shin, Hsu Pei-Chen, Chen Chao-Chun, Chin Yu-Ting, Huang Tai-Lin, Hsu Yuan-Nian, Kuo Chien-Chung, Wang Yun-Chi, Tsai Chia-Wen, Gong Chi-Li, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Mounting evidence has shown that miRNAs play a critical role in the regulation of hematopoiesis of cell proliferation and apoptosis as well as in tumorigenesis. The miR146a rs2910164 polymorphism, which is closely responsive for its expression, has been reported to associate with the risk of several solid cancers. The study aimed at examining the association of the it with susceptibility to...

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PMID: 32108040
DOI: 10.21873/cgp.20178
PMCID: PMC7078834

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