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Article

Association between polymorphisms in microRNA biosynthesis genes and acute lymphoblastic leukemia susceptibility in Chinese children and adolescents.

Personalized medicine - 1 Apr 2026

Cao Xiaoqing, Wang Lingyun, Kang Yurou, Tai Ping, Chen Nayun, Liu Yang, Yang Yanli, Fang Daihua, He Bangshun

Abstract excerpt

AIM: This study investigated associations between SNPs in miRNA-related genes (DROSHA, DGCR8, AGO1, TNRC6B) and acute lymphoblastic leukemia (ALL) susceptibility in Chinese children and adolescents. METHODS: A case-control study of 360 patients and 398 matched controls was conducted. Genotyping used the MassARRAY platform, and multifactor dimensionality reduction (MDR) assessed potential SNP-SNP interactions....

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Identifiers

PMID: 41923653
DOI: 10.1080/17410541.2026.2653871

Genes

DGCR8
DROSHA
AGO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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