Article
Lack of Association between the MiR146a Polymorphism and Susceptibility to Thai Childhood Acute Lymphoblastic Leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Chansing Kochpinchon, Pakakasama Samart, Hongeng Suradej, Thongmee Acharawan, Pongstaporn Wanida
Abstract excerpt
BACKGROUND: MiRNAs, small non coding RNAs, play a role in the regulation of hematopoiesis, with effects on cell growth, differentiation, and apoptosis. In addition, MiRNAs are thought to play an important role in tumorigenesis. The miR146a G>C polymorphism can lead to alteration of miR146 expression, which appears to be associated with development and progression of several cancers. This study aimed to...
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