Article
Hsa-miR-196a2 polymorphism increases the risk of acute lymphoblastic leukemia in Chinese children.
Mutation research - 1 Jan 2014
Tong Na, Xu Bin, Shi Danni, Du Mulong, Li Xin, Sheng Xiaojing, Wang Meilin, Chu Haiyan, Fang Yongjun, Li Jie, Wu Dongmei, Zhang Zhengdong
Abstract excerpt
Acute lymphoblastic leukemia (ALL) is a major cause of mortality and morbidity in childhood, and the causes of ALL are not completely understood. microRNAs (miRNAs) regulate various biological processes including organ development, cell growth regulation, cell differentiation, apoptosis, and tumorigenesis. We performed a case-control study with 570 childhood ALL cases and 673 cancer-free controls to investigate...
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