Article
Analysis of Killer Immunoglobulin-Like Receptor Genes in Colorectal Cancer.
Cells - 24 Feb 2020
Diaz-Peña Roberto, Mondelo-Macía Patricia, Molina de la Torre Antonio José, Sanz-Pamplona Rebeca, Moreno Víctor, Martín Vicente
Abstract excerpt
Natural killer cells (NK cells) play a major role in the immune response to cancer. An important element of NK target recognition is the binding of human leucocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs). Colorectal carcinoma (CRC) is one of the most common types of inflammation-based cancer. The purpose of the present study was to investigate the presence of KIR genes and...
Topics
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Colorectal Neoplasms
- Female
- Genotype
- Humans
- Killer Cells, Natural
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
