KIR genes and HLA class I ligands in a Caucasian Brazilian population with colorectal cancer.

doi:10.1016/j.humimm.2017.01.003

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Article

KIR genes and HLA class I ligands in a Caucasian Brazilian population with colorectal cancer.

Human immunology - 1 Mar 2017

Portela Pâmela, Merzoni Joice, Lindenau Juliana D, Damin Daniel C, Wilson Timothy John, Roesler Rafael, Schwartsmann Gilberto, Jobim Luiz Fernando, Jobim Mariana

Abstract excerpt

Colorectal cancer (CRC) can occur anywhere in the colon or rectum and represents the third most common cancer in the world in both sexes. Natural killer cells (NK) are part of the innate immune system recognizing class I HLA molecules on target cells through their membrane receptors, called killer cell immunoglobulin-like receptors (KIR). The aim of our study was to evaluate the association between the KIR genes...

Topics

Aged
Brazil
Colorectal Neoplasms
Female
Gene Frequency
Genotype
HLA Antigens
HLA-A Antigens
HLA-B Antigens
HLA-C Antigens
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Ligands

Linkage Disequilibrium

Male

Middle Aged

Odds Ratio

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 28088355
DOI: 10.1016/j.humimm.2017.01.003

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