Article
HLA-Cw polypmorphism and killer cell immunoglobulin-like receptor (KIR) gene analysis in Korean colorectal cancer patients.
International journal of surgery (London, England) - 1 Jan 2014
Kim Hyung-Jin, Choi Hae-Baeg, Jang Jung-Pil, Baek In-Cheol, Choi Eun-Jeong, Park Miyoung, Kim Tai-Gyu, Oh Seong-Taek
Abstract excerpt
PURPOSE: Natural killer cells (NK cells) play important roles in protecting the patient from the early development of cancers, and are activated or inhibited by killer cell immunoglobulin-like receptors (KIR), which bind to HLA class I. In the present study, we investigated the KIR genotype of Korean colorectal cancer patients. METHODS: DNA samples were extracted from peripheral blood cell samples taken from...
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