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Article

Killer-cell immunoglobulin-like receptor genes and ligands and their role in hematologic malignancies.

Cancer immunology, immunotherapy : CII - 1 Apr 2016

Varbanova Viktoria, Naumova Elissaveta, Mihaylova Anastasiya

Abstract excerpt

Natural killer (NK) cells are considered crucial for the elimination of emerging tumor cells. Effector NK-cell functions are controlled by interactions of inhibitory and activating killer-cell immunoglobulin-like receptors (KIRs) on NK cells with human leukocyte antigen (HLA) class I ligands on target cells. KIR and HLA are highly polymorphic genetic systems segregating independently, creating a great diversity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26874942
DOI: 10.1007/s00262-016-1806-9
PMCID: PMC11029164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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