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Shared genetic susceptibilities for irritable bowel syndrome and depressive disorder in Chinese patients uncovered by pooled whole-exome sequencing

30 Jan 2020

Abstract excerpt

Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder presenting a high comorbidity with depressive disorder (DD). Many studies have confirmed that these two disease share the similar pathophysiological process, but evidence of the genetic risks is limited. This study aimed to analyze the genetic susceptibilities for IBS and DD in Chinese patients. Pooled whole-exome sequencing...

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Congenital gastrointestinal and neural anomalies
Gastrointestinal motility and disorders
Helicobacter pylori-related gastroenterology studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32099673
DOI: 10.1016/j.jare.2020.01.016

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