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Article

Unraveling the genetic susceptibility of irritable bowel syndrome: integrative genome-wide analyses in 845 492 individuals: a diagnostic study

14 Aug 2024

Abstract excerpt

BACKGROUND: Irritable bowel syndrome (IBS) significantly impacts individuals due to its prevalence and negative effect on quality of life. Current genome-wide association studies (GWAS) have only identified a small number of crucial single nucleotide polymorphisms (SNPs), not fully elucidating IBS's pathogenesis. OBJECTIVE: To identify genomic loci at which common genetic variation influences IBS susceptibility....

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PMID: 39166955
DOI: 10.1097/js9.0000000000002039

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