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Integrated omics analysis reveals the epigenetic mechanism of visceral hypersensitivity in IBS-D

16 Mar 2023

Abstract excerpt

Background and objective: IBS-D is a common functional bowel disease with complex etiology and without biomarker. The pathological and physiological basis of IBS-D focuses on visceral hypersensitivity. However, its epigenetic mechanism remains elusive. Our study aimed to integrate the relationship between differentially expressed miRNAs, mRNAs and proteins in IBS-D patients in order to reveal epigenetic mechanism...

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PMID: 37007011
DOI: 10.3389/fphar.2023.1062630

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