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Article

Causal relationships between psychological disorders and functional gastrointestinal disorders: a bidirectional two-sample Mendelian randomization study.

European journal of gastroenterology & hepatology - 1 Nov 2024

Liu Tangyi, Wang Zeyu, Kang Xiaoyu, Wang Xiangping, Ren Gui, Lv Yong, Li Jing, Liu Yaling, Liang Shuhui, Nie Yongzhan, Luo Hui, Pan Yanglin

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have shown bidirectional associations between psychological disorders (e.g. depression and anxiety) and functional gastrointestinal disorders. However, whether the relationships are causal is uncertain. Here, we used a bidirectional two-sample Mendelian randomization method to investigate the association between psychological disorders and functional gastrointestinal...

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Identifiers

PMID: 38973539
DOI: 10.1097/MEG.0000000000002825

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