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Article

The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children.

Bioscience reports - 28 Feb 2020

Wang Juxiang, Lou Susu, Huang Xiaokai, Mo Yixiao, Wang Zhen, Zhu Jinhong, Tian Xiaoqian, Shi Jiandong, Zhou Haixia, He Jing, Ruan Jichen

Abstract excerpt

Wilms tumor is the most common pediatric malignancy in the kidney. The miR34b/c is a downstream target gene of the transcription factor p53. The important role of TP53 mutations, the methylation of miR34b/c, and the interaction between these two molecules in tumorigenesis have been well documented. Due to the biological connection between p53 and miR34b/c, in the present study, we investigated the association...

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Identifiers

PMID: 32083300
DOI: 10.1042/BSR20194202
PMCID: PMC7048686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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