Article
Association between PHOX2B gene rs28647582 T>C polymorphism and Wilms tumor susceptibility.
Bioscience reports - 30 Oct 2019
Lin Ao, Fu Wen, Wang Wenwen, Zhu Jinhong, Liu Jiabin, Xia Huimin, Liu Guochang, He Jing
Abstract excerpt
Wilms tumor is one of the most common pediatric solid tumors. The pair-like homeobox 2b (PHOX2B) gene is an important transcription factor that regulates cellular proliferation and differentiation in early life. The association between PHOX2B single nucleotide polymorphisms (SNPs) and Wilms tumor risk has not been investigated. Therefore, we conducted a case-control study involving 145 Wilms tumor patients and...
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