A potentially functional polymorphism in the promoter region of miR-34b/c is associated with renal cell cancer risk in a Chinese population.

doi:10.1093/mutage/geu001

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Article

A potentially functional polymorphism in the promoter region of miR-34b/c is associated with renal cell cancer risk in a Chinese population.

Mutagenesis - 1 Mar 2014

Zhang Shaobo, Qian Jian, Cao Qiang, Li Pu, Wang Meilin, Wang Jian, Ju Xiaobing, Meng Xiaoxin, Lu Qiang, Shao Pengfei, Zhang Zhengdong, Qin Chao, Yin Changjun

Abstract excerpt

Members of the miR-34 family have been shown to be transcriptional targets of the tumour suppressor gene P53. Aberration expression of miR-34 impairs p53-mediated cell cycle arrest and apoptosis. A single nucleotide polymorphism T > C (rs4938723) located within the CpG island in the promoter regi...

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PMID: 24503183
DOI: 10.1093/mutage/geu001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24503183-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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