Article
Association of TP53 rs1042522 C>G and miR-34b/c rs4938723 T>C polymorphisms with hepatoblastoma susceptibility: A seven-center case-control study.
The journal of gene medicine - 1 Jul 2020
Liu Peng, Zhuo Zhen-Jian, Zhu Jinhong, Yang Zhonghua, Xin Yijuan, Li Suhong, Li Li, Li Yong, Wang Huaili, He Jing
Abstract excerpt
BACKGROUND: Hepatoblastoma is a rare malignancy originating from pluripotent stem cells with unknown etiology. An understanding of the etiology in pediatric hepatoblastoma has been hampered by the unavailability of sufficient patient samples. To date, only a few epidemiological studies with small sample sizes have been performed investigating risk factors for hepatoblastoma. TP53 and pri-miR-34b/c genes are...
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