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Article

Association Between Arg72Pro Polymorphism in TP53 and Malignant Abdominal Solid Tumor Risk in Hunan Children.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Liu Zan, Xiao Zhenghui, Li Ming, Xiao Yaling, Wang Xiyang, He Jing, Li Yong

Abstract excerpt

Pediatric solid tumors are heterogeneous and comprise various histological subtypes. TP53, a tumor suppressor, orchestrates the transcriptional activation of anti-cancer genes. The gene coding for this protein is highly polymorphic, and its mutations are associated with cancer development. The Arg72Pro polymorphism in TP53 has been associated with susceptibility to various types of cancer. Here, in this...

Topics

Abdominal Neoplasms
Adolescent
Arginine
Case-Control Studies
Female
Genetic Predisposition to Disease
Genotype
Humans
Male
Neuroblastoma
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 33759598
DOI: 10.1177/10732748211004880
PMCID: PMC8204553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Association Between Arg72Pro Polymorphism in TP53 and Malignant Abdominal Solid Tumor Risk in Hunan Children.PMID 33759598Read ↗

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