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YTHDC1 gene polymorphisms and Wilms tumor susceptibility in Chinese children: A five-center case-control study.

Gene - 30 May 2021

Lin Ao, Hua Rui-Xi, Zhou Mingming, Fu Wen, Zhang Jiao, Zhou Haixia, Li Suhong, Cheng Jiwen, Zhu Jinhong, Xia Huimin, Liu Guochang, He Jing

Abstract excerpt

Wilms tumor is a common pediatric tumor with abundant genetic drivers. YTHDC1 is an important reader of the N6-methyladenosine modification that widely regulates eukaryotic transcripts. YTHDC1 has been associated with the occurrence and development of some tumors. However, this is the first study on YTHDC1 gene polymorphisms and Wilms tumor susceptibility. In brief, we conducted a five-center case-control study...

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PMID: 33737126
DOI: 10.1016/j.gene.2021.145571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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