Article
Histone H3 serine 57 and lysine 56 interplay in transcription elongation and recovery from S-phase stress.
PloS one - 26 May 2010
Aslam Aamir, Logie Colin
Abstract excerpt
BACKGROUND: Acetylation of lysine 56 of histone H3 plays an important role in the DNA damage response and it has been postulated to play an as yet undefined role in transcription, both in yeast and in higher eukaryotes. Because phosphorylated human histone H3 serine 57 peptides have been detected by mass spectrometry we examined whether H3-S57 phosphorylation interplays with H3-K56 acetylation in vivo....
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