Article
Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks.
Molecular & cellular proteomics : MCP - 1 Sept 2018
Cheng Li, Liu Cheng-Xi, Jiang Shuangying, Hou Sha, Huang Jin-Guo, Chen Zi-Qing, Sun Yang-Yang, Qi Huan, Jiang He-Wei, Wang Jing-Fang, Zhou Yi-Ming, Czajkowsky Daniel M, Dai Junbiao, Tao Sheng-Ce
Abstract excerpt
Proteins, as the major executer for cell progresses and functions, its abundance and the level of post-translational modifications, are tightly monitored by regulators. Genetic perturbation could help us to understand the relationships between genes and protein functions. Herein, to explore the impact of the genome-wide interruption on certain protein, we developed a cell lysate microarray on kilo-conditions...
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