Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic characterization reveals a simple histone H4 acetylation code.

Proceedings of the National Academy of Sciences of the United States of America - 12 Apr 2005

Dion Michael F, Altschuler Steven J, Wu Lani F, Rando Oliver J

Abstract excerpt

The histone code hypothesis holds that covalent posttranslational modifications of histone tails are interpreted by the cell to yield a rich combinatorial transcriptional output. This hypothesis has been the subject of active debate in the literature. Here, we investigated the combinatorial complexity of the acetylation code at the four lysine residues of the histone H4 tail in budding yeast. We constructed yeast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Histones

Share to Lysine

Share to Multigene Family

Share to Oligonucleotide Array Sequence Analysis

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 15795371
DOI: 10.1073/pnas.0500136102
PMCID: PMC555684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic characterization reveals a simple histone H4 acetylation code.PMID 15795371Read ↗

KAT8 beyond Acetylation: A Survey of Its Epigenetic Regulation, Genetic Variability, and Implications for Human Health.Semantic proximity Read ↗

Single residue changes to the histone core catalyze neofunctionalization and impose fitness trade-offsSemantic proximity Read ↗

Natural single-nucleosome epi-polymorphisms in yeast.Semantic proximity Read ↗

A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress.Semantic proximity Read ↗

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing.Semantic proximity Read ↗

Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.Semantic proximity Read ↗

A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation.Semantic proximity Read ↗

A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation.Semantic proximity Read ↗

Regulators of cellular levels of histone acetylation in Saccharomyces cerevisiae.Semantic proximity Read ↗

N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing.Semantic proximity Read ↗

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and EukaryotesSemantic proximity Read ↗

Nucleosome alterations caused by mutations at modifiable histone residues in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.