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Article

Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome.

Human molecular genetics - 30 Apr 2021

McGurk Kathryn A, Williams Simon G, Guo Hui, Watkins Hugh, Farrall Martin, Cordell Heather J, Nicolaou Anna, Keavney Bernard D

Abstract excerpt

Signalling lipids of the N-acyl ethanolamine (NAE) and ceramide (CER) classes have emerged as potential biomarkers of cardiovascular disease (CVD). We sought to establish the heritability of plasma NAEs (including the endocannabinoid anandamide) and CERs, to identify common DNA variants influencing the circulating concentrations of the heritable lipids, and assess causality of these lipids in CVD using 2-sample...

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Identifiers

PMID: 33437986
DOI: 10.1093/hmg/ddab002
PMCID: PMC8101358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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