Article
GWAS in cancer: progress and challenges.
Molecular genetics and genomics : MGG - 1 May 2020
Liang Baiqiang, Ding Hongrong, Huang Lianfang, Luo Haiqing, Zhu Xiao
Abstract excerpt
The genome-wide association study (GWAS) is an effective method to detect single-nucleotide polymorphisms (SNPs) of multiple individual genes based on linkage disequilibrium (LD). GWAS examines genotypes and distinguishing gene characteristics that are exhibited in diseases. In the past few decades, more and more literature has reported the results of applying GWAS to study tumors. Although many pleiotropic loci...
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