Article
Lessons from postgenome-wide association studies: functional analysis of cancer predisposition loci.
Journal of internal medicine - 1 Nov 2013
Monteiro A N A, Freedman M L
Abstract excerpt
In the last few years, genome-wide association studies (GWASs) have identified hundreds of predisposition loci for several types of human cancers. Recent progress has been made in determining the underlying mechanisms through which different single-nucleotide polymorphisms (SNPs) affect predisposition to cancer. Although there has been much debate about the clinical utility of GWASs, less attention has been paid...
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