Article
Genome-wide association studies of cancer: principles and potential utility.
Oncology (Williston Park, N.Y.) - 1 Jun 2010
Stadler Zsofia K, Gallagher David J, Thom Peter, Offit Kenneth
Abstract excerpt
Genome-wide association studies (GWAS) have emerged as a new approach for investigating the genetic basis of complex diseases. In oncology, genome-wide studies of nearly all common malignancies have been performed and more than 100 genetic variants associated with increased risks have been identified. GWAS approaches are powerful research tools that are revealing novel pathways important in carcinogenesis and...
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