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Article

α-Synuclein oligomers in skin biopsy of idiopathic and monozygotic twin patients with Parkinson's disease.

Brain : a journal of neurology - 1 Mar 2020

Mazzetti Samanta, Basellini Milo J, Ferri Valentina, Cassani Erica, Cereda Emanuele, Paolini Matilde, Calogero Alessandra M, Bolliri Carlotta, De Leonardis Mara, Sacilotto Giorgio, Cilia Roberto, Cappelletti Graziella, Pezzoli Gianni

Abstract excerpt

A variety of cellular processes, including vesicle clustering in the presynaptic compartment, are impaired in Parkinson's disease and have been closely associated with α-synuclein oligomerization. Emerging evidence proves the existence of α-synuclein-related pathology in the peripheral nervous system, even though the presence of α-synuclein oligomers in situ in living patients remains poorly investigated. In this...

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Identifiers

PMID: 32025699
DOI: 10.1093/brain/awaa008
PMCID: PMC7089656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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