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Article

Peripheral synucleinopathy in Parkinson disease with LRRK2 G2385R variants.

Annals of clinical and translational neurology - 1 Mar 2021

Yang Jing, Wang Hao, Yuan Yanpeng, Fan Shiheng, Li Lanjun, Jiang Chenyang, Mao Chengyuan, Shi Changhe, Xu Yuming

Abstract excerpt

OBJECTIVE: Recent studies demonstrated cutaneous phosphorylated α synuclein (p-syn) deposition in idiopathic and some monogenetic Parkinson disease (PD) patients, suggesting synucleinopathy identical to that in the brain. Although the LRRK2 Gly2385Arg (G2385R) variant is a common PD risk factor in the Chinese population, the pathogenesis of PD with G2385R variant has not been reported. We investigated whether...

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Identifiers

PMID: 33527742
DOI: 10.1002/acn3.51301
PMCID: PMC7951097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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