Article
Transglutaminase orthologues in medaka fish - biochemical characterization and establishment of gene-deficient mutants.
Analytical biochemistry - 1 Sept 2020
Meng Qi, Watanabe Yuko, Suzuki Risa, Oguri Rina, Tatsukawa Hideki, Hitomi Kiyotaka
Abstract excerpt
By genome analysis, seven homologous genes (orthologues) of human transglutaminases (TGases) have been identified in medaka fish (Oryzias latipes), some of which clearly corresponded to Factor XIII, TG1, and TG2. The enzymatically active-recombinant proteins for these medaka TGases have been successfully produced in bacteria or baculovirus-infected insect cell systems. Specific antibodies have been prepared and...
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