Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases.

Bioscience, biotechnology, and biochemistry - 1 Jul 2018

Watanabe Yuko, Furukawa Eri, Tatsukawa Hideki, Hashimoto Hisashi, Kamei Yasuhiro, Taniguchi Yoshihito, Hitomi Kiyotaka

Abstract excerpt

Transglutaminase (TG) is an essential enzyme to catalyze cross-linking reactions of epidermal proteins. Recently, we biochemically characterized human skin TG orthologues for medaka (Oryzias latipes), a model fish. By genome editing, gene-modified fishes for the two orthologues were obtained, both of which lack the ordinal enzymes. These fish appeared to exhibit higher susceptibility to osmolality at the period...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Fish Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Editing

Share to Oryzias

Share to Osmolar Concentration

Share to Transglutaminases

Source

Identifiers

PMID: 29570037
DOI: 10.1080/09168451.2018.1453294

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases.PMID 29570037Read ↗

Gene disruption of medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2) causes movement retardation.Semantic proximity Read ↗

Transglutaminase orthologues in medaka fish - biochemical characterization and establishment of gene-deficient mutants.Semantic proximity Read ↗

A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation.Semantic proximity Read ↗

The <i>O</i> -GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stressSemantic proximity Read ↗

The medaka <i>alg2</i> mutant is a model for hypo- <i>N</i> -glycosylation-associated retinitis pigmentosaSemantic proximity Read ↗

The Caenorhabditis elegans mucin-like protein OSM-8 negatively regulates osmosensitive physiology via the transmembrane protein PTR-23.Semantic proximity Read ↗

Production of a tributyltin-binding protein 2 knockout mutant strain of Japanese medaka, <i>Oryzias latipes</i>Semantic proximity Read ↗

Zebrafish as a model system to study heritable skin diseases.Semantic proximity Read ↗

Establishing an auxin-inducible GFP nanobody-based acute protein knockdown system to mimic hypomorphic mutations during early medaka embryogenesisSemantic proximity Read ↗

Effects of Deficient Glycosylation and Deglycosylation on Sperm Condition in Zebrafish ( <i>Danio rerio</i> )Semantic proximity Read ↗

Mutations at key pore-lining positions differentiate the water permeability of fish lens aquaporin from other vertebrates.Semantic proximity Read ↗

The see-through medaka: a fish model that is transparent throughout life.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.