Article
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 1996
Bugge T H, Xiao Q, Kombrinck K W, Flick M J, Holmbäck K, Danton M J, Colbert M C, Witte D P, Fujikawa K, Davie E W, Degen J L
Abstract excerpt
Tissue factor (TF) is the cellular receptor for coagulation factor VI/VIIa and is the membrane-bound glycoprotein that is generally viewed as the primary physiological initiator of blood coagulation. To define in greater detail the physiological role of TF in development and hemostasis, the TF ge...
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