Article
Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors.
Aging - 3 Feb 2020
Ma Yunlong, Li Jingjing, Xu Yi, Wang Yan, Yao Yinghao, Liu Qiang, Wang Maiqiu, Zhao Xinyi, Fan Rongli, Chen Jiali, Zhang Bin, Cai Zhen, Han Haijun, Yang Zhongli, Yuan Wenji, Zhong Yigang, Chen Xiangning, Ma Jennie Z, Payne Thomas J, Xu Yizhou, Ning Yuping, Cui Wenyan, Li Ming D
Abstract excerpt
The prevalence of smoking is significantly higher in persons with schizophrenia (SCZ) than in the general population. However, the biological mechanisms of the comorbidity of smoking and SCZ are largely unknown. This study aimed to reveal shared biological pathways for the two diseases by analyzing data from two genome-wide association studies with a total sample size of 153,898. With pathway-based analysis, we...
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