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Multi-Trait Genetic Insights Into Schizophrenia Across Ancestries: Genome-Wide Association Meta-Analyses, Machine Learning, and Drug Repurposing Study.

Brain and behavior - 1 Jul 2026

Yan Ping, Wang Haili, Shu Ye, Xie Rui, Reyidan Ainiwaner, Fu Songnian

Abstract excerpt

BACKGROUND: Schizophrenia is a psychiatric disorder characterized by a wide range of symptoms and a complex interplay between genetic and environmental factors. Despite advances in genomics, the genetic underpinnings of SC and its relationship with drug use remain poorly understood. METHODS: This study utilized genome-wide association data from 53,386 SC patients and 77,258 controls of mainly European ancestry,...

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PMID: 42421611
DOI: 10.1002/brb3.71594
PMCID: PMC13347149

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