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Article

Genome-wide identification of the shared genetic basis of cannabis and cigarette smoking and schizophrenia implicates NCAM1 and neuronal abnormality.

Psychiatry research - 1 Apr 2022

Song Weichen, Lin Guan Ning, Yu Shunying, Zhao Min

Abstract excerpt

OBJECTIVES: Confirming the existence and composition of the shared genetic basis of Schizophrenia and cannabis and cigarette smoking has critical values for the clinical prevention and intervention of psychosis. METHODS: To achieve this goal, we leveraged Genome-Wide summary statistics of Schizophrenia (n = 99,934), cigarette smoking (n = 518,633) and cannabis usage (n = 162,082). We applied Causal Analysis Using...

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PMID: 35235886
DOI: 10.1016/j.psychres.2022.114453

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