Article
Association between polygenic liability for schizophrenia and substance involvement: A nationwide population-based study in Taiwan.
Genes, brain, and behavior - 1 Jun 2020
Wang Shi-Heng, Lai Rou-Yi, Lee Ya-Chin, Su Mei-Hsin, Chen Chia-Yen, Hsiao Po-Chang, Yang Albert C, Liu Yu-Li, Tsai Shih-Jen, Kuo Po-Hsiu
Abstract excerpt
Schizophrenia and substance involvement frequently co-occur in individuals, and a bidirectional relationship between the two has been proposed; shared underlying genetic factors could be an alternative explanation. This study investigated the genetic overlap between schizophrenia and substance involvement, including tobacco, alcohol and betel nut use. The study subjects were recruited from the Taiwan Biobank, and...
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