Is the TAP2 single nucleotide polymorphism rs241447 truly associated with psoriasis in Poles?

doi:10.1016/j.humimm.2020.01.005

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Article

Is the TAP2 single nucleotide polymorphism rs241447 truly associated with psoriasis in Poles?

Human immunology - 1 Jan 2000

Wiśniewski Andrzej, Wilczyńska Karolina, Wagner Marta, Jasek Monika, Niepiekło-Miniewska Wanda, Nowak Izabela, Matusiak Łukasz, Szczerkowska-Dobosz Aneta, Kuśnierczyk Piotr

Abstract excerpt

Psoriasis vulgaris (PsV) is strongly associated with HLA-C*06:02. HLA class I molecules present antigenic peptides to CD8+ T lymphocytes. Peptide transport from cytosol to the endoplasmic reticulum is mediated by a transporter associated with antigen processing (TAP) composed of TAP1 and TAP2 polymorphic proteins. Here, we compared the distribution of three coding single nucleotide polymorphisms (SNPs), rs1057141...

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PMID: 32008813
DOI: 10.1016/j.humimm.2020.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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