Article
Polymorphisms in HLA-related genes and psoriasis heredity in patients with psoriasis.
International journal of dermatology - 1 Aug 2013
Vasku Anna, Bienertova-Vasku Julie, Izakovicova-Holla Lydie, Pavkova Goldbergova Monika, Kozacikova Zuzana, Splichal Zbynek, Vasku Vladimir
Abstract excerpt
BACKGROUND: The aim of this study was to investigate possible associations of the five DNA polymorphic genotypes in the HLA region (transporter associated with antigen processing [TAP1; TAP1 333 a/b, TAP1 637 c/d], the HLA-DRB1*1501-rs3135388, tumor necrosis factor [TNF]α [-238 G/A] and NcoI TNFβ) with characteristics of family history in patients with psoriasis vulgaris. MATERIALS AND METHODS: A total of 201...
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