Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes.

doi:10.1034/j.1399-0039.1999.530203.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes.

Tissue antigens - 1 Feb 1999

Jenisch S, Westphal E, Nair R P, Stuart P, Voorhees J J, Christophers E, Krönke M, Elder J T, Henseler T

Abstract excerpt

Although psoriasis vulgaris (PsV) is strongly associated with certain human leukocyte antigens, the pathogenetic nature of these associations remains elusive. The objectives of this study were: (i) to determine whether HLA loci directly determine susceptibility or merely serve as markers for the susceptibility allele; and (ii) to identify additional disease-associated haplotypes. By applying maximum likelihood...

Topics

Alleles
Female
Gene Frequency
Genetic Diseases, Inborn
Haplotypes
Humans
Linkage Disequilibrium
Major Histocompatibility Complex
Male
Pedigree
Psoriasis

Source

Open in PubMed

Identifiers

PMID: 10090613
DOI: 10.1034/j.1399-0039.1999.530203.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics