Article
Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes.
Tissue antigens - 1 Feb 1999
Jenisch S, Westphal E, Nair R P, Stuart P, Voorhees J J, Christophers E, Krönke M, Elder J T, Henseler T
Abstract excerpt
Although psoriasis vulgaris (PsV) is strongly associated with certain human leukocyte antigens, the pathogenetic nature of these associations remains elusive. The objectives of this study were: (i) to determine whether HLA loci directly determine susceptibility or merely serve as markers for the susceptibility allele; and (ii) to identify additional disease-associated haplotypes. By applying maximum likelihood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.