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Article

SWI/SNF Complex Mutations in Gynecologic Cancers: Molecular Mechanisms and Models.

Annual review of pathology - 24 Jan 2020

Wang Yemin, Hoang Lien, Ji Jennifer X, Huntsman David G

Abstract excerpt

The SWI/SNF (mating type SWItch/Sucrose NonFermentable) chromatin remodeling complexes interact with histones and transcription factors to modulate chromatin structure and control gene expression. These evolutionarily conserved multisubunit protein complexes are involved in regulating many biological functions, such as differentiation and cell proliferation. Genomic studies have revealed frequent mutations of...

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Source

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Identifiers

PMID: 31977292
DOI: 10.1146/annurev-pathmechdis-012418-012917
PMCID: PMC6986318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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