Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Opening and changing: mammalian SWI/SNF complexes in organ development and carcinogenesis.

Open biology - 1 Oct 2024

Abu Sailik Fadia, Emerald Bright Starling, Ansari Suraiya Anjum

Abstract excerpt

The switch/sucrose non-fermentable (SWI/SNF) subfamily are evolutionarily conserved, ATP-dependent chromatin-remodelling complexes that alter nucleosome position and regulate a spectrum of nuclear processes, including gene expression, DNA replication, DNA damage repair, genome stability and tumour suppression. These complexes, through their ATP-dependent chromatin remodelling, contribute to the dynamic regulation...

Topics

Humans
Animals
Chromatin Assembly and Disassembly
Carcinogenesis
Neoplasms
Chromosomal Proteins, Non-Histone
Transcription Factors
Organogenesis
Mutation
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 39471843
DOI: 10.1098/rsob.240039
PMCID: PMC11521604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-39471843-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Opening and changing: mammalian SWI/SNF complexes in organ development and carcinogenesis.PMID 39471843Read ↗

Advances in the role of SWI/SNF complexes in tumours.Semantic proximity Read ↗

The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early developmentSemantic proximity Read ↗

Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunitiesSemantic proximity Read ↗

The SWI/SNF Complex: A Frequently Mutated Chromatin Remodeling Complex in Cancer.Semantic proximity Read ↗

SWI/SNF chromatin remodeling and human malignancies.Semantic proximity Read ↗

SWI/SNF nucleosome remodellers and cancer.Semantic proximity Read ↗

The role of SWI/SNF complexes in digestive system neoplasms.Semantic proximity Read ↗

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities.Semantic proximity Read ↗

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.Semantic proximity Read ↗

BAFfling pathologies: Alterations of BAF complexes in cancer.Semantic proximity Read ↗

SWI/SNF chromatin-remodeling complexes in cardiovascular development and disease.Semantic proximity Read ↗

Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.