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Article

Detection of 6pLOH in an aplastic anemia patient by in phase HLA genotyping.

HLA - 1 May 2020

Kikkawa Eri, Shiina Takashi, Shigenari Atsuko, Ozaki Yuki, Suzuki Shingo, Ando Kiyoshi, Onizuka Makoto

Abstract excerpt

Recent studies have reported loss of heterozygosity in the chromosome 6p arms (6pLOH) of acquired aplastic anemia (AA) patients, and in tumor cells trying to escape the autoimmune system. We thus sought to establish detection methods for LOH to investigate the mechanisms underlying AA and tumor immunity. Herein, we report our evaluation of 6pLOH in a patient with severe AA patient using super-high resolution,...

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PMID: 31970935
DOI: 10.1111/tan.13807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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