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Article

The Importance of Confirming False Homozygosity in Pretransplant HLA Typing Results of Patients with Hematologic Malignancies.

International journal of medical sciences - 1 Jan 2024

Lee Min Young, You Eunkyoung

Abstract excerpt

Loss of heterozygosity (LOH) on chromosome 6p, where the HLA genes are located, can result in incorrect homozygosity findings during HLA genotyping in patients with hematologic malignancies. The degree of HLA compatibility between donor and recipient is crucial in hematopoietic stem cell transplantation. Therefore, we present a case of false homozygosity in HLA genotyping due to LOH on chromosome 6p in a patient...

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Share to Chromosomes, Human, Pair 6
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

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Share to HLA Antigens

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 39439464
DOI: 10.7150/ijms.99883
PMCID: PMC11492872

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