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Article

Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia.

Blood - 25 May 2017

Zaimoku Yoshitaka, Takamatsu Hiroyuki, Hosomichi Kazuyoshi, Ozawa Tatsuhiko, Nakagawa Noriharu, Imi Tatsuya, Maruyama Hiroyuki, Katagiri Takamasa, Kishi Hiroyuki, Tajima Atsushi, Muraguchi Atsushi, Kashiwase Koichi, Nakao Shinji

Abstract excerpt

To identify HLA alleles closely involved in the autoantigen presentation in acquired aplastic anemia (AA), we studied the HLA allelic loss frequencies of 312 AA patients, including 43 patients with loss of heterozygosity of 6p chromosome (6pLOH). An analysis of the HLA alleles contained in the lost haplotype revealed HLA-B*40:02 to be the most frequently lost allele. When we examined 28 AA (12 6pLOH[+] and 16...

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Identifiers

PMID: 28232583
DOI: 10.1182/blood-2016-11-752378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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