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Article

Criteria to define HLA haplotype loss in human solid tumors.

Tissue antigens - 1 May 2000

Ramal L M, Feenstra M, van der Zwan A W, Collado A, Lopez-Nevot M A, Tilanus M, Garrido F

Abstract excerpt

Short tandem repeat (STR) markers are currently used to define loss of heterozygosity (LOH) of genes and chromosomes in tumors. Chromosome 6 and chromosome 15 STR markers are applied to define loss of HLA and related genes (e.g. TAP and beta2m). The number of STR identified in the HLA region is still increasing. In this study, seven representative STR markers covering the 6p/6q arms of chromosome 6 including the...

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Share to Biomarkers, Tumor
Share to Chromosomes, Human, Pair 15
Share to Chromosomes, Human, Pair 6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

Share to Loss of Heterozygosity

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Source

Identifiers

PMID: 10885565
DOI: 10.1034/j.1399-0039.2000.550507.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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