Article
Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function.
Journal of human genetics - 1 Apr 2020
Ding Qiuju, Tan Amelia Li Min, Parra E J, Cruz Miguel, Sim Xueling, Teo Yik-Ying, Long Jirong, Alsafar Habiba, Petretto Enrico, Tai E-Shyong, Chen Huimei
Abstract excerpt
Genome-wide association studies (GWASs) have identified many genetic variations associated with type 2 diabetes mellitus (T2DM) in Asians, but understanding the functional genetic variants that influence traits is often a complex process. In this study, fine mapping and other analytical strategies were performed to investigate the effects of G protein signaling modulator 1 (GPSM1) on insulin resistance in...
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