Article
Genome-wide association study identifies three novel loci for type 2 diabetes.
Human molecular genetics - 1 Jan 2014
Hara Kazuo, Fujita Hayato, Johnson Todd A, Yamauchi Toshimasa, Yasuda Kazuki, Horikoshi Momoko, Peng Chen, Hu Cheng, Ma Ronald C W, Imamura Minako, Iwata Minoru, Tsunoda Tatsuhiko, Morizono Takashi, Shojima Nobuhiro, So Wing Yee, Leung Ting Fan, Kwan Patrick, Zhang Rong, Wang Jie, Yu Weihui, Maegawa Hiroshi, Hirose Hiroshi, Kaku Kohei, Ito Chikako, Watada Hirotaka, Tanaka Yasushi, Tobe Kazuyuki, Kashiwagi Atsunori, Kawamori Ryuzo, Jia Weiping, Chan Juliana C N, Teo Yik Ying, Shyong Tai E, Kamatani Naoyuki, Kubo Michiaki, Maeda Shiro, Kadowaki Takashi
Abstract excerpt
Although over 60 loci for type 2 diabetes (T2D) have been identified, there still remains a large genetic component to be clarified. To explore unidentified loci for T2D, we performed a genome-wide association study (GWAS) of 6 209 637 single-nucleotide polymorphisms (SNPs), which were directly genotyped or imputed using East Asian references from the 1000 Genomes Project (June 2011 release) in 5976 Japanese...
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