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Functional genetic variants and susceptibility and prediction of gestational diabetes mellitus.

Scientific reports - 5 Aug 2024

Huang Gongchen, Sun Yan, Li Ruiqi, Mo Lei, Liang Qiulian, Yu Xiangyuan

Abstract excerpt

The aetiological mechanism of gestational diabetes mellitus (GDM) has still not been fully understood. The aim of this study was to explore the associations between functional genetic variants screened from a genome-wide association study (GWAS) and GDM risk among 554 GDM patients and 641 healthy controls in China. Functional analysis of single nucleotide polymorphisms (SNPs) positively associated with GDM was...

Topics

Humans
Diabetes, Gestational
Female
Pregnancy
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease
Adult
Genome-Wide Association Study
Risk Factors
China
Case-Control Studies

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Identifiers

PMID: 39103437
DOI: 10.1038/s41598-024-69079-y
PMCID: PMC11300845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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