Article
Cis-regulation of antisense non-coding RNA at the JAZF1 locus in type 2 diabetes.
The journal of gene medicine - 1 Apr 2022
Ding Qiuju, Zhao Weiwei, Long Jirong, Alsafar Habiba, Zhou Qing, Chen Huimei
Abstract excerpt
BACKGROUND: Several genomic loci of type 2 diabetes (T2D) nominated in genome-wide association studies (GWAS) have been suggested to regulate metabolism in muscle. However, a large portion of the genetic risk and the underlying regulation remain unexplained. The present study aimed to localize the potentially functional regions or genes at juxtaposed with another zinc finger protein 1 (JAZF1) locus and interpret...
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