Article
Common variants of SLAMF1 and ITLN1 on 1q21 are associated with type 2 diabetes in Indian population.
Journal of human genetics - 1 Mar 2012
Tabassum Rubina, Mahajan Anubha, Dwivedi Om Prakash, Chauhan Ganesh, Spurgeon Charles J, Kumar M V Kranthi, Ghosh Saurabh, Madhu S V, Mathur Sandeep K, Chandak Giriraj R, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
Though multiple studies link chromosomal regions 1q21-q23 and 20q13 with type 2 diabetes, fine mapping of these regions is yet to confirm gene(s) explaining the linkages. These candidate regions remain unexplored in Indians, which is a high-risk population for type 2 diabetes. Hypothesizing regulatory regions to have a more important role in complex disorders, we examined association of 207 common variants in...
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